Coagulopathy in Cardiac Surgery; a Quaternary-care Academic Center Experience
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 398
- 试验地点
- 2
- 主要终点
- incidence of coagulopathy after cardiac surgery in Thai people
研究概览
简要总结
Coagulopathy in cardiac surgery; a quaternary-care academic center experience
Objectives:
Primary:
To determine incidence of coagulopathy after cardiac surgery in Thai people To determine incidence of resternotomy for stop bleeding, morbidity and mortality
Secondary:
To identify risk factors which associated with non-red cell transfusion and coagulopathy
study decide: Retrospective chart review
详细描述
Data to be collected:
Age*, gender* Body weight, height, body mass index* Underlying disease: DM, renal disease*, liver disease* Pre-op. Antiplatelet or anticoagulant* Pre-op coagulogram and platelet count* Emergency or elective surgery Resternotomy or not* Intraoperative blood component Intraoperative factor concentration Dose and timing of antifibrinolytic administration* CPB time* Postoperative body temperature*
*Possible risk factors for non-red cell transfusion
statistic: To assess the relationship between risk factors and non-red cell transfusion a univariate analysis was performed using an unpaired t-test and a Chi-square test.
For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ≥ 18 years
- •Schedule to cardiac surgery under cardiopulmonary bypass
排除标准
- •Schedule for aortic surgery or complex congenital cardiac surgery
- •Using ECMO before surgery
- •Incomplete anesthetic record
结局指标
主要结局
incidence of coagulopathy after cardiac surgery in Thai people
时间窗: 1 year
coagulopathy and throbocytopenia
次要结局
未报告次要终点
研究者
Chaowanan Khamtuikrua
lecturer
Mahidol University