Coagulopathy in Cardiac Surgery

Completed

• Conditions: Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass

• Registration Number: NCT03475940
• Lead Sponsor: Mahidol University

Brief Summary

Coagulopathy in cardiac surgery; a quaternary-care academic center experience

Objectives:

Primary:

To determine incidence of coagulopathy after cardiac surgery in Thai people To determine incidence of resternotomy for stop bleeding, morbidity and mortality

Secondary:

To identify risk factors which associated with non-red cell transfusion and coagulopathy

study decide: Retrospective chart review

Detailed Description

Data to be collected:

Age\*, gender\* Body weight, height, body mass index\* Underlying disease: DM, renal disease\*, liver disease\* Pre-op. Antiplatelet or anticoagulant\* Pre-op coagulogram and platelet count\* Emergency or elective surgery Resternotomy or not\* Intraoperative blood component Intraoperative factor concentration Dose and timing of antifibrinolytic administration\* CPB time\* Postoperative body temperature\*

\*Possible risk factors for non-red cell transfusion

statistic: To assess the relationship between risk factors and non-red cell transfusion a univariate analysis was performed using an unpaired t-test and a Chi-square test.

For higher accuracy regarding the impact of single risk factors, a multiple logistic regression analysis was also performed.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2017-12-31
• Study First Submitted: 2017-12-31
• Study First Submitted QC: 2018-03-17
• Study First Posted: 2018-03-23
• Primary Completion: 2019-06-30
• Study Completion: 2020-06-30
• Status Verified: 2020-11
• Last Update Submitted: 2020-11-16
• Last Update Posted: 2020-11-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 398

Inclusion Criteria

• Age ≥ 18 years
• Schedule to cardiac surgery under cardiopulmonary bypass

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Exclusion Criteria

• Schedule for aortic surgery or complex congenital cardiac surgery
• Using ECMO before surgery
• Incomplete anesthetic record

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
incidence of coagulopathy after cardiac surgery in Thai people	1 year	coagulopathy and throbocytopenia

Trial Locations

Locations (2)

faculty of medicine Siriraj hospital; 🇹🇭 Bangkok, Thailand

Faculty of medicine Siriraj hospital; 🇹🇭 Bangkok Noi, Bangkok, Thailand