A Randomized Controlled Trial Using Turmeric for Patients With Basal Joint Arthritis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Change in baseline pain intensity
Study Overview
Brief Summary
The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 40 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •40 years of age or older
- •English fluency and literacy
- •Seeking care for basal joint pain
- •Tender over basal joint
- •Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
- •Radiographic evidence of Eaton stage 1 and 2 only
Exclusion Criteria
- •Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
- •Inability or unwillingness to participate in a trial study
- •Rheumatoid Arthritis or other inflammatory disorder diagnoses
- •Post-traumatic osteoarthritis
- •Patients on Coumadin/Steroids/NSAIDs/Tylenol
- •Diabetes Mellitus
- •Pregnant or lactating women
- •Basal joint arthritis of Eaton stage 3
- •Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)
Arms & Interventions
Control
Subjects in this group will receive a placebo pill 3 times per day for 6 weeks.
Intervention: Placebo (Other)
Turmeric
Subjects in this group will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.
Intervention: Turmeric (Dietary Supplement)
Outcomes
Primary Outcomes
Change in baseline pain intensity
Time Frame: Enrollment, 6 weeks, and 3 months
0-10 ordinal rating of pain intensity
Change in baseline disability
Time Frame: Enrollment, 6 weeks, and 3 months
Disability measured by the QuickDASH
Secondary Outcomes
No secondary outcomes reported
Investigators
Neal Chung-Jen Chen
Medical Doctor
Massachusetts General Hospital