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Clinical Trials/NCT02842060
NCT02842060
Completed
Not Applicable

Development of a Tailored HIV Prevention Intervention for Young Men

University of Pennsylvania1 site in 1 country180 target enrollmentNovember 2016
ConditionsHIV Infections

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV Infections
Sponsor
University of Pennsylvania
Enrollment
180
Locations
1
Primary Endpoint
Number of Participants With Change in Number of Risky Sexual Partnerships
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

This study uses an interactive design and development process to develop tailored messages that align YMSM's relationship experiences and desires with HIV prevention strategies. The study includes a tailored online prevention, intervention, as well as an attention control non--tailored HIV prevention (NTHP) comparison intervention. The pilot RCT will compare the intervention (N=120) to NTHP (N=60) to assess intervention feasibility and acceptability, and gather preliminary behavioral data to inform a subsequent application. Follow-up assessments will be collected at thirty (30), sixty (60), and ninety (90) days post-intervention.

Detailed Description

A resurgence of new HIV cases among young men who have sex with men (YMSM; ages 18--24) has underscored the importance of developing culturally- and developmentally- informed HIV programs for YMSM. The investigators are developing and pilot testing a tailored, web- based intervention called myDEx that focuses on delivering HIV prevention messages based on single YMSM's relationship expectations and partner--seeking behaviors. To maximize intervention appeal and appropriateness, the investigators have convened a youth advisory board (YAB) to provide insight and feedback during the 3--stage intervention development process. Using an iterative design and development process, they have developed tailored messages that align YMSM's relationship experiences and desires with HIV prevention strategies. The investigators designed and developed the myDEx tailored online prevention intervention, as well as an attention- control non--tailored HIV/AIDS prevention (NTHP) comparison intervention. After developing both interventions, the investigators used usability testing procedures to collect preliminary data from 16 YMSM on the proposed intervention's design and acceptability. Recommended changes were added to the intervention prior to launching a small pilot randomized controlled trial (RCT). The pilot RCT will compare myDEx (N=120) to NTHP (N=60) to assess intervention feasibility and acceptability, and gather preliminary behavioral data to inform a subsequent application. Assessments will be collected at 30, 60, and 90 days follow--up. Specific Aims include: 1. To develop a tailored (myDEx) and non-tailored (NTHP) HIV prevention intervention focused on addressing HIV risk behaviors among single YMSM; 2. To collect preliminary data on the feasibility, acceptability, and intervention content of the myDEx (N=16) in preparation for a small pilot RCT; and, 3. To implement a small pilot RCT of the refined myDEx (N=120) as compared to the NTHP (N=60) intervention, in order to evaluate its feasibility and acceptability and gather preliminary efficacy results in reducing sexual risk behaviors.

Registry
clinicaltrials.gov
Start Date
November 2016
End Date
May 2017
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jose Bauermeister

Presidential Associate Professor of Nursing

University of Pennsylvania

Eligibility Criteria

Inclusion Criteria

  • Cis-gender male
  • Self-report as being single
  • Self report as HIV-negative at baseline
  • Speak and read English
  • Report unprotected anal intercourse with a male partner in prior six (6) months
  • Have access to computer or smartphone device

Exclusion Criteria

  • Transgender identity
  • HIV positive diagnosis
  • Not residing in the United States
  • Does not engage in male-to-male sexual behavior

Outcomes

Primary Outcomes

Number of Participants With Change in Number of Risky Sexual Partnerships

Time Frame: Count of participants from baseline to 90-day follow-up reported

The investigators estimated the change in the total number of participants who reported engaging in condomless anal intercourse from baseline to 90-day follow-up.

Number of Participants With Change in HIV Testing Behavior

Time Frame: Count of participants from baseline to 90-day follow-up reported

The investigators estimated the number of participants who reported testing for HIV from baseline to 90-day follow-up.

Secondary Outcomes

  • Change in Self-efficacy Motivations to Engage in HIV Prevention Behaviors(Baseline to 90-day follow-up period)
  • Changes in Psychological Well-being(Baseline to 90-day follow-up period)

Study Sites (1)

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