Midazolam plasma concentration in children after anesthesia premedication in clinical routine
- Conditions
- Children undergoing surgery in General anesthesia
- Registration Number
- DRKS00008736
- Lead Sponsor
- Institut für Anästhesie und IntensivmedizinKantonsspital Frauenfeld
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Elective surgery in general anesthesia, estimated Duration of surgery less than 31 min, midazola 0.5 mg/kg clinically indicated, written informed parental consent
Exclusion Criteria
Allergy to any used substances, severe respiratory/neurological/liver/kidney(gastro-intestinal Problems, medication known to interfere with midazolam pharmakocinetics, OSAS, application of midazolam during study period other than per study protocol.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Midazolam plasma Levels at induction of anesthesia and at the end of operations.
- Secondary Outcome Measures
Name Time Method evel of sedation upon arrival in the OR (OAA/S). Next day: Rating of sedation level (VAS) and of satisfaction with premedication (VAS) by parents.<br>