EEG Measurements to Capture DBS-induced Electric Potentials
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Electric potential at the EEG locations
研究概览
简要总结
To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (>100 kHz).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Provision of written informed consent by the patient
- •Age 35 - 85
- •patient groups: Parkinson's disease, essential tremor, dystonia
- •>3 months after surgery for DBS
排除标准
- 未提供
结局指标
主要结局
Electric potential at the EEG locations
时间窗: during DBS
The investigators will extract the DBS pulses from the EEG data and check the distribution of the electric potentials as seen in simulations based on individual MRI and CT images. Parameters of the simulation pipeline (e.g. conductances) will be adjusted so that the simulation models fit the data.
次要结局
未报告次要终点