Multi drug resistant staphyloccocus aureus as nasal carriage in healthy individuals of tertiary care center.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- This study will assessed to identify carrier rates and virulence markers of nasal S.aureus.to determine the presence of MDR S.aureus.to detect antimicrobial susceptibility pattern of isolates.
研究概览
简要总结
The pathogenicity of Staphylococcus aureus is influenced by two important features: its ability to resist more
than three classes of antibiotics and the capacity to produce several toxins. The worldwide increase in multidrug-resistant bacteria is a worrying phenomenon that is mainly associated with the lack of development of new antibacterial compounds. This increase is linked to the abundant use of antibiotics in humans as well as animals. This multidrug resistance concerns a large variety of microorganisms, both specific and opportunistic pathogens. When these bacteria migrate to usually sterile
sites, they can cause different types of infection. This type of evolution from healthy carriage to infection is typical for nosocomial infection. Staphylococcus aureus (including Methicillin-resistant Staphylococcus aureus ) frequently colonizes the human skin and the upper respiratory tract. This study will be a prospective study to assess the drug resistance of staphyloccocus aureus from nasal swabs in healthy individuals.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 15.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •All the healthy individuals with age from greater than 15 yrs old and less than 55 yrs old were included in this study.
排除标准
- •Children with the age less than 15 years will be excluded for this study.
- •Old age individuals with age greater than 55 yrs old will be excluded.
- •Any individuals with acute or cronic infection will be excluded.
结局指标
主要结局
This study will assessed to identify carrier rates and virulence markers of nasal S.aureus.to determine the presence of MDR S.aureus.to detect antimicrobial susceptibility pattern of isolates.
时间窗: Assessments will be done at 12 months
次要结局
未报告次要终点
研究者
Prajakta Gajanan Nimbalkar
Datta Meghe Institute of Higher Education and Research