Effect of Iranian traditional medicine remedy on chemotherapy induced nausea and vomiting

Phase 2

Completed

• Conditions: nausea vomiting; Breast cancer, Traditional medicine, Chemotherapy Induced Nausea and Vomiting(CINV), Rhus Coriaria, Bunium Persicum

• Registration Number: TCTR20160401004
• Lead Sponsor: Vice of research, Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-03-17
• Study Start: 2016-04-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 62

Inclusion Criteria

Female, Definitive diagnosis of breast cancer by oncologists and a pathology report by pathologists, Age>18 years, History of chemotherapy induced nausea and vomiting resistant to conventional therapy, Normal tests for CBC, urea, creatinine, Alt, Ast, Bilirubin, FBS, Na, K, Have at least three sessions of chemotherapy ahead.

Exclusion Criteria

Total or upper abdominal radiation therapy along with chemotherapy- Taking anticoagulants, Use of other drugs/therapy for nausea and vomiting that not prescribed in this study, Hypersensitivity to Sumac or Bunium Persicum, Use of sumac and Bunium Persicum in seven days prior to the intervention, Diseases of the digestive system, Diseases that may associate with nausea and vomiting (such as hypertension, liver failure and kidney, digestive problems), Milk allergy, Losing of two consecutive or three intermittent doses of intervention.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of nausea in acute phase first 24 hour after intervention number,Frequency of nausea in delayed phase 24 hour to fifth day after intervention number,Frequency of vomiting in acute phase first 24 hour after intervention number,Frequency of vomiting in delayed phase 24 hour to fifth day after intervention number,severity of nausea in acute phase first 24 hour after intervention number,severity of nausea in delayed phase 24 hour to fifth day after intervention number,severity of vomiting in acute phase first 24 hour after intervention number,severity of vomiting in delayed phase 24 hour to fifth day after intervention number

Secondary Outcome Measures

Name	Time	Method
Frequency of nausea in delayed phase Day 2-5 of intervention number,Frequency of vomiting in delayed phase Day 2-5 of intervention number,severity of nausea in delayed phase Day 2-5 of intervention number,severity of vomiting in delayed phase Day 2-5 of intervention number