Pulsed Dye Laser for the Psoriatic Nail

Completed

• Conditions: Psoriatic Nail

• Registration Number: NCT01303185
• Lead Sponsor: Taipei Medical University WanFang Hospital

Brief Summary

The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.

Detailed Description

Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2011-02-22
• Study First Submitted QC: 2011-02-23
• Study First Posted: 2011-02-24
• Primary Completion: 2012-02
• Study Completion: 2012-02
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-11
• Last Update Posted: 2014-12-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Psoriatic nail refractory to other topical and systemic treatment therapy
• ≧ 16 years old

Exclusion Criteria

• Patient with pregnancy
• Patient with photo sensitivity
• Patient with severe wound around finger nails or paronychia
• Patient with hypersensitivity to Tazarotene cream

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
global physician assessment	3rd and 6th months
NAPSI	3rd and 6th months

Trial Locations

Locations (1)

Taipei Medical University - WanFang Hospital; 🇨🇳 Taipei, Taiwan