跳至主要内容
临床试验/CTRI/2025/07/090353
CTRI/2025/07/090353尚未招募不适用

Efficacy of topical Samagh-e-Arabi (Acacia Arabica Willd) with Sirka (Vinegar) in Quba Mutaqashshir (Tinea Corporis)A Non-Randomized Clinical Trial

Government Of Tamilnadu1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年7月18日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Reduction in Total Sign and Symptom Score (TSSS).

研究概览

简要总结

Tinea corporis, known as Quba in Unani medicine, refers to superficial fungal infections affecting the skin, excluding the scalp, beard, face, hands, feet and groin. It presents as circular erythematous scaly and hypopigmented patches with central clearing, forming characteristic ring like lesions called Ringworm. Dermatophytes infect the keratinized stratum corneum but cannot penetrate deeper tissues. In Unani medicine, Quba also called Karyun or Dad, is caused by mirrha-e-sawda or abnormal black bile and involves the body natural forces. Quwwat-i-Tabaiyya diverts harmful humor or Khilt-i-Bad to the skin. Symptoms include roughness, itching, scaling, and dry lesions that may appear blackish, reddish, or pus-filled depending on the causative agents. Globally, tinea infections affect twenty to twenty five percent of the population with high prevalence in India. Males are more susceptible due to outdoor exposure, heat, and friction. According to the Unani system of medicine, the treatment of Quba focuses on the causative factors, such as Akhlat, and the disease intensity, duration, and clinical signs. Numerous Traditional healers have also suggested medications with Mudammil-e-Quruh (healing) and Musaffi-i-dam (blood purifier).Unani physicians have placed a strong focus on topical treatment using products like Zimad (paste), Tila (liniment), and Marham (ointment). Conventional medicine relies on antifungals and corticosteroids, but increasing resistance and recurrence highlight the need for safer alternatives. This study evaluates Samagh-e-Arabi (Acacia Arabica) with Sirka (vinegar), a Unani formulation from Kitabul Umda fil Jarahat, as a potential remedy for Quba. The aim is to provide an effective traditional therapeutic option amid rising antifungal resistance and economic burdens in dermatophytosis management.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Circumscribed lesions on trunk and limbs with itching, erythema, scales, central clearing with peripheral raised margins.
  • Participants diagnosed with Positive Mycology (KOH positive).

排除标准

  • Patients below the Age of 18 Years and above the age of 60 Years.
  • Participants suffering from severe systemic or metabolic diseases.
  • Participants suffering from concomitant conditions, or diseases like Psoriasis, Eczema Pregnant Or Lactating Women.
  • Participants not willing to follow the protocol.

结局指标

主要结局

Reduction in Total Sign and Symptom Score (TSSS).

时间窗: Total Sign and Symptom Score (TSSS):7th day,14th day,21st day,28th day | KOH examination: Baseline,28th day

KOH Examination:

时间窗: Total Sign and Symptom Score (TSSS):7th day,14th day,21st day,28th day | KOH examination: Baseline,28th day

Complete Elimination of fungal elements in KOH examination at the 28th day of treatment in comparison to baseline

时间窗: Total Sign and Symptom Score (TSSS):7th day,14th day,21st day,28th day | KOH examination: Baseline,28th day

次要结局

未报告次要终点

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Patel Hafsa Nooruddin

Government Unani Medical College

研究点 (1)

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