The Influence on SPecific Activity of protein S and coagulation system : Dienogest and low dose estrogen-progestin for Endometriosis. - The Influence on SPecific Activity of protein S and coagulation system : Dienogest and low dose estrogen-progestin for Endometriosis. (SPADE)

Department of Obstetrics and Gynecology, Kyushu University Hospital0 个研究点目标入组 200 人开始时间: 2016年5月10日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1. Patients with pregnant or the possibility of pregnancy. 2. Patients with post partum within 4 weeks or with lactation. 3. Patients with abnormal genital bleeding not to be diagnosed. 4. Patients with the complication of malignant tumor or the suspicion of complication. 5. Patients with severe hepatic disorder or hepatic tumor. 6. Patients within 4 weeks after the operation (excluding operational duration of less than 30 min). 7. Patients without continuous administration for 24 weeks. 8. Patients with treatment history of steroidal hormones including sex hormones and GnRH agonist within the past 3 months. 9. Patients under anticoagulation and antiplatelet drug. 10. Patients with hypersensitivity to the constituents of the study drug (dienogest tablets or low dose estrogen-progestin tablets). 11. Patients with contraindication of Lunabell tablet LD/ULD and Yaz tablet in low dose estrogen-progestin group. 12. Patient who is judged to be inappropriate for study participation for any reason by the doctor.

发起方

Department of Obstetrics and Gynecology, Kyushu University Hospital