Effects of Different Percentages Body Weight Supported Treadmill Training on Gait, Balance, Quality of Life and Fatigue in Parkinson's Disease: A Double Blind Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- Hitit University
- Enrollment
- 35
- Locations
- 1
- Primary Endpoint
- 6 Minute Walk Test (6MWT)
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Body weight supported treadmill training (BWSTT) is an important rehabilitative choice for neurologically impaired subjects such as Parkinson's disease (PD). The aim of the study is to evaluate the effectiveness of different percentages BWSTT on gait, balance, quality of life and fatigue in moderate to advanced PD.
Detailed Description
Body weight supported treadmill training (BWSTT) is an important rehabilitative choice for neurologically impaired subjects such as Parkinson's disease (PD). The aim of the study is to evaluate the effectiveness of different percentages BWSTT on gait, balance, quality of life and fatigue in moderate to advanced PD. Thirty five patients were randomly assigned to one of the three groups according to the percentage unweighed: 0% BWSTT, 10% BWSTT and 20% BWSTT. All patients participated 30 minutes BWSTT sessions 5 days a week, for 6 weeks. Primary outcomes were 6 minute walk test (6MWT), Berg balance scale (BBS), Unified Parkinson's Disease Rating Scale (UPDRS); and secondary outcomes were Nottingham health profile (NHP), Fatigue Impact Scale (FIS) and Fatigue Severity Scale (FSS) which were performed at the beginning and end of the rehabilitation.
Investigators
Tuğba Atan
Assoc. Prof.
Hitit University
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of Parkinson's disease according to the UK Brain Bank criteria.
- •Subjects had clinically moderate to advanced severity of disease (Hoehn and Yahr stage 2 - 4).
- •Subjects whose medical treatment had been on stable dosage of dopaminomimetics for at least 4 weeks before the study.
- •Subjects ability to walk with or without assistive device.
Exclusion Criteria
- •Subjects had cardiovascular, inflammatory or musculoskeletal problems that could prevent them to participate in an exercise program.
- •Subjects whose mini mental status examination score was less than 26.
Outcomes
Primary Outcomes
6 Minute Walk Test (6MWT)
Time Frame: 6 weeks
Functional exercise capacity was assessed by distance walked in 6 minutes (6MWT). The patient was asked to walk as long as possible for 6 minutes on a 30 meters of marked and flat ground, at a self selected speed. 6MWT is a submaximal exercise test and can be used to assess treatment response .
Berg Balance Scale (BBS):
Time Frame: 6 weeks
It contains 14 instructions and 0 - 4 points is given for each instruction according to the performance of the patients. 0 points are given when the patient totally could not do the activity while 4 points are given when the patient completes the activity independently.
Unified Parkinson's Disease Rating Scale (UPDRS):
Time Frame: 6 weeks
It is used to follow the clinical status of PD. It consists of four main parts (totally 183 points): mentation, behavior and mood (UPDRS I: 16 points), activities of daily living (UPDRS II: 52 points), motor examination (UPDRS III: 92 points), treatment complications (UPDRS IV: 23 points).
Secondary Outcomes
- Nottingham Health Profile (NHP):(6 weeks)
- Fatigue Impact Scale (FIS):(6 weeks)
- Fatigue Severity Scale (FSS):(6 weeks)