Association of Plasma Pentraxin 3 Concentration With Angiographic and Clinical Outcomes in STEMI Treated by Primary Angioplasty
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 335
- 试验地点
- 1
- 主要终点
- The proportion of thrombus grade 4&5 and final TIMI flow <3
研究概览
简要总结
335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.
详细描述
335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute STEMI with symptom onset <12 h undergoing primary PCI
排除标准
- •Acute STEMI patients who received fibrinolytic therapy
结局指标
主要结局
The proportion of thrombus grade 4&5 and final TIMI flow <3
时间窗: Intraprocedure
PTX3 concentration was compared based on the outcome
次要结局
未报告次要终点
研究者
Surya Dharma
Primary Investigator
Indonesian Cardiovascular Research Center