Study to evaluate the effect of chondroitin sulfate on the synovitis in patients with knee osteoarthritis

Completed

• Conditions: Osteoarthritis; Musculoskeletal Diseases

• Registration Number: ISRCTN64282813
• Lead Sponsor: Hospital del Mar (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-11-20
• Last Update Posted: 6 July 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

1. Men or women 40 years or older
2. Fulfilment of the American College of Rheumatology (ACR) classification criteria for clinical KOA
3. Presence of radiographic OA in the knee joint, defined as a Kellgren and Lawrence (K&L) score of 2 or 3.
4. Ultrasonography presence of synovitis plus joint effusion thickness =4 mm

Exclusion Criteria

1. Any serious disease (such as decompensate heart disease, diabetes, fibromyalgia, renal insufficiency, liver disease or malignancies)
2. Secondary OA
3. Use of any medication already know to affect the variables examined (oral corticosteroids, intra-articular corticosteroids, or any SYSADOA within 3 previous months before study enrolment, or any nonsteroidal anti-inflammatory drug within 30 days before study?s enrolment)

Study & Design

• Study Type: Interventional
• Study Design: Not specified