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TREASURE trial

Phase 1
Recruiting
Conditions
Subclinical heart failure
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Registration Number
CTIS2022-503135-33-00
Lead Sponsor
niversity Hospital Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
130
Inclusion Criteria

Women, aged 18 years and older, Heart failure stage-B or diastolic dysfunction, Premenopausal, with or without a history of preeclamptic pregnancy, =½ and = 30 years after the (first) (complicated) pregnancy;, Last delivery at least 6 months ago

Exclusion Criteria

Already using antihypertensive medication, Systolic blood pressure of =180 mmHg and/or diastolic blood pressure of =110 mmHg, Suffering diabetes mellitus, kidney failure (GFR<60 ml/min/1.73m2), pre-existent auto-immune disease and/or liver insufficiency, Women have the intention to pursue pregnancy within 2 years (as ACE inhibitors may be teratogenic), Breastfeeding during participation, Auto-immune disease(s) prior to the (complicated) pregnancy, Chronic hypertension prior to the complicated pregnancy, Women who do not want themselves and/or their general practitioner and specialist(s) to be informed about the test results

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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