Adjuvant Radiotherapy in breast cancer using Volumetric Modulated Arc Therapy (VMAT) technique: dosimetric comparison with 3D-Conformal Radiotherapy, and report on clinical outcomes.

Kasturba Medical College Manipal0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•Patients with breast cancer requiring adjuvant radiotherapy following either BCS or MRM, but cannot be adequately treated with 3D-CRT, and thereby require IMRT based RT planning. Criteria:
•a.Tumor coverage V95 < 90%.
•b.Homogeneity Index > 0.1.
•c.V105 > 5% of the tumor.
•d.V10 <15-20% of heart.
•e.Ipsilateral lung dose <25%.
•f.Internal mammary lymph node positive cases.
•g.B/L breast cancer.
•Willing to participate in the study and provides a voluntary informed consent.

•1. Metastatic disease, and patients being considered for loco-regional radiotherapy with an intent to palliation.
•2. History of prior radiation, connective tissue disorders or other comorbidities that could put the patient at higher risk of developing treatment related toxicities.

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