Characterisation of COVID-19 long-term immunity
- Conditions
- COVID-19 (SARS-CoV-2 infection)Infections and Infestations
- Registration Number
- ISRCTN11946807
- Lead Sponsor
- niversity of Bristol
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 372
Participants of the ALSPAC cohort meeting the following criteria:
1. Aged 25 or over
2. Undergone SARS-CoV-2 antibody testing through the ALSPAC SARS-CoV-2 serology study (IRAS 289493)
3. Individuals who, through self-report or through linkage to official health records, are identified as being highly likely to have had COVID-19 infection (from either positive SARS-CoV-2 PCR test performed at NHS care facility, COVID-19 testing site or home testing)
4. Individuals who have been told by a physician that, in the opinion of that doctor, they have had a clinical illness likely to be COVID-19
Control participants
5. Aged 25 or over
6. Individuals who self-report as not experiencing symptoms of COVID-19 via the symptom survey
7. Self-report as not having had positive SARS-CoV-2 molecular test
8. Are confirmed SARS-CoV-2 seronegative at Visit 1
Exclusion criteria for both controls and cases:
1. Do not wish to participate in this research study
2. Participants taking blood thinners or blood-thinning agents (e.g. warfarin) or with a known clotting disorder or other reason unable to provide a blood sample
3. Not willing to provide blood samples
4. Do not meet eligibility criteria for respective arm
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method