Randomized Controlled Clinical Trial To Evaluate The Add On Effect Of Navaka Guggulu Along With Thyroxine In Hypothyroidism
试验速览
- 阶段
- Phase 3 4
- 状态
- 招募中
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- 1 Weight gain/month
研究概览
简要总结
Hypothyroidism is a hypo metabolic clinical state resulting from inadequate production of thyroid hormones for prolonged periods or rarely, from resistance of the peripheral tissues to the effects of thyroid hormones. Its incidence is increasing day by day and its name became common on the tongue of society. It effects the body Physiology as well as psychology. It occurs about five times more often in females than in males1. In the vast majority of cases Hypothyroidism (approximately 99%) results from an intrinsic disorder of the thyroid gland (primary Hypothyroidism)
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
入选标准
- •Known case of Hypothyroidism. 3) Gender.
- •both male and female patients will be selected irrespective of religions and economical status.
排除标准
- •1.Patients suffering from co-morbid or life threatening eliments.
- •2.Congenital hypothyroidism or anatomical deformity related to thyroid gland 3.Known case of thyroid neoplasia.
- •4.Progressive case of myxoedema coma.
- •5.Infiltrative disorders like sarcoidosis etc 6.Individual suffering from immune compromised diseases or patients on immunocompressive drugs.
- •7.Pregnancy.
结局指标
主要结局
1 Weight gain/month
时间窗: Inclusion day, 30th day, 60th day, 90th day.
2 Amennorrhea
时间窗: Inclusion day, 30th day, 60th day, 90th day.
3 Loss of appetite
时间窗: Inclusion day, 30th day, 60th day, 90th day.
4 Constipation
时间窗: Inclusion day, 30th day, 60th day, 90th day.
5
时间窗: Inclusion day, 30th day, 60th day, 90th day.
Hoarseness of voice
时间窗: Inclusion day, 30th day, 60th day, 90th day.
6 Somnolence (Duration of sleep)
时间窗: Inclusion day, 30th day, 60th day, 90th day.
7 Dyspnoea
时间窗: Inclusion day, 30th day, 60th day, 90th day.
8 Quantity of menstrual flow
时间窗: Inclusion day, 30th day, 60th day, 90th day.
9 Duration of menstrual bleeding
时间窗: Inclusion day, 30th day, 60th day, 90th day.
10 Debility
时间窗: Inclusion day, 30th day, 60th day, 90th day.
11Dryness of skin
时间窗: Inclusion day, 30th day, 60th day, 90th day.
12Hair loss
时间窗: Inclusion day, 30th day, 60th day, 90th day.
13. Thyroid Function test
时间窗: Inclusion day, 30th day, 60th day, 90th day.
次要结局
- Adverse effect of the Ayurvedic drug if any.(Inclusion day, 30th day, 60th day, 90th day.)
研究者
Dr Revati Pradeep Dhawadkar
MAMs Sumatibhai Shah Ayurved Mahavidyalaya Malwadi Hadapsar Pune
