Effect of celecoxibe added to sertralin in patients with moderate to severe depressio
Phase 1
- Conditions
- Major Depression.Severe depressive episode without psychotic symptoms
- Registration Number
- IRCT138903124090N1
- Lead Sponsor
- ational Iranian Oil Company Health Organization
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Inclusion Criteria:
1. Major Depression according to DSM IV and Hamilton Depression Scale(HamD)
2. 18 y < age > 50 y
Exclusion Criteria
1. Having psychotic disorders
2. Receiving anti-depressant drugs during last month
3. Receiving ECT during last two months
4. Having thyroid disorder
5. Having Cardiovascular disorders
6. Pregnancy
7. Breast Feeding
8. Age <18 y
9. Age > 50 y
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Depression. Timepoint: 0, 2, 4, 6 weeks intervals. Method of measurement: Hamilton depression scale.
- Secondary Outcome Measures
Name Time Method Antidepressants and Celxocibe side effects. Timepoint: 0, 2, 4 and 6 weeks intervals. Method of measurement: drug side effects check list.