NCT07169721已完成不适用
CIRCAdian Rhythm of the IMMune Age IndeX (CIRCA-IMMAX) - Influence of Circadian Rhythm on the Determination of an Immune Age Metric
Leibniz Research Centre for Working Environment and Human Factors1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2023年12月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Changes in the Immune Age Index Immune Age Index (IMMAX) from morning to midday and evening
研究概览
简要总结
The goal of this observational study is to evaluate the influence of circadian rhythms on the determination of an individual's immune age. The biomarker IMMAX was calculated for 50 participants aged 20-69 at 8 a.m., 1 p.m. and 6 p.m. on the same day.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •aged > 18 years
- •knowledge of German or English sufficient to provide verbal explanations and obtain written consent
排除标准
- •exercise on the assessment day
- •acute infection
- •vaccination within the last 4 weeks
- •autoimmune disease
- •drugs that may influence immune cell counts
- •participation in other interventional studies during study period
结局指标
主要结局
Changes in the Immune Age Index Immune Age Index (IMMAX) from morning to midday and evening
时间窗: From 8 a.m. until 6 p.m. on the same day
To determine the Immune Age Index, 100 µl blood is collected and immunostained with antibodies. The immune cells are then analyzed using flow cytometry. IMMAX values range from 0 to 1 with higher values indicating a higher immune age.
次要结局
未报告次要终点
研究者
研究点 (1)
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