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The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium

Completed
Conditions
Post-tetanic Count on One Arm, the Other Arm is the Control
Interventions
Device: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
Registration Number
NCT01086176
Lead Sponsor
Maisonneuve-Rosemont Hospital
Brief Summary

The purpose of this study is to see how long does the effect of a post-tetanic facilitation last on subsequent train-of-four. The investigators hypothesis is that the effect last at least 30 minutes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • Patient having general anesthesia in dorsal decubitus with both arm available for at least an hour and a half
Exclusion Criteria
  • Age >75 or <18
  • Neuromuscular disease
  • difficult laryngoscopy predicted
  • Allergy to rocuronium
  • Malignant hyperthermia
  • Full stomach
  • Drugs the influence neuromuscular blockers
  • Decision of the clinician to exclude his patient

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patient-controlNMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)-
Primary Outcome Measures
NameTimeMethod
The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%
Secondary Outcome Measures
NameTimeMethod
The difference at 30 minutes after the post-tetanic count on the T1% (of the calibrated T1) in both arms, we expect a difference of more than 10%
The difference of the slope of recuperation on TOF and T1% after a post-tetanic count vs the control arm that had no tetanic stimulation

Trial Locations

Locations (1)

Hopital Maisonneuve-Rosemont

🇨🇦

Montréal, Quebec, Canada

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