NCT01086176CompletedNot Applicable
The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium
Maisonneuve-Rosemont Hospital1 site in 1 country22 target enrollmentStarted: March 2010Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 22
- Locations
- 1
- Primary Endpoint
- The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%
Study Overview
Brief Summary
The purpose of this study is to see how long does the effect of a post-tetanic facilitation last on subsequent train-of-four. The investigators hypothesis is that the effect last at least 30 minutes.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient having general anesthesia in dorsal decubitus with both arm available for at least an hour and a half
Exclusion Criteria
- •Age >75 or <18
- •Neuromuscular disease
- •difficult laryngoscopy predicted
- •Allergy to rocuronium
- •Malignant hyperthermia
- •Full stomach
- •Drugs the influence neuromuscular blockers
- •Decision of the clinician to exclude his patient
Outcomes
Primary Outcomes
The difference at 30 minutes after the post-tetanic count between the TOF% in both arms, we expect a difference of more than 10%
Secondary Outcomes
- The difference at 30 minutes after the post-tetanic count on the T1% (of the calibrated T1) in both arms, we expect a difference of more than 10%
- The difference of the slope of recuperation on TOF and T1% after a post-tetanic count vs the control arm that had no tetanic stimulation
Investigators
Study Sites (1)
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