Development of AI Diagnosis System for T1b Colorectal Cancer on Non-magnified Plain Endoscopic Images
Not Applicable
- Conditions
- Early stage colorectal cancer (Tis/T1a/T1b) receiving colonoscoppy between 2016 Jan. and 2018 Dec.
- Registration Number
- JPRN-UMIN000037053
- Lead Sponsor
- Fukushima Medical University
- Brief Summary
At 90% cutoff for per-lesion score, the CADx system showed the highest specificity of 94.4% [95% confidence interval: 91.3-96.6], with 59.8% [48.3-70.4] sensitivity and 87.3% [83.7-90.4] accuracy. The area under the characteristic curve was 85.1% [79.9-90.4] for CADx, 88.2% [83.7-92.8] for expert 1, 85.9% [80.9-90.9] for expert 2, 77.0% [71.5-82.4] for trainee 1 (CADx vs. trainee 1: p=0.0076), and 66.2% [60.6-71.9] for trainee 2 (CADx vs. trainee 2: p<0.0001).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 1513
Inclusion Criteria
Not provided
Exclusion Criteria
1) Pedunculated morphology 2) Huge lesion, >5cm in size 3) Chromoendoscopic images 4) Images enhanced by NBI, BLI etc.
Study & Design
- Study Type
- Others,meta-analysis etc
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Specificity for T1b colorectal cancer
- Secondary Outcome Measures
Name Time Method Sensitivity, PPV, NPV and overall accuracy for T1b colorectal cancer