Muscles in Motion: Exercise rehabilitation for children and adolescents with Juvenile Dermatomyositis

Completed

Conditions: Juvenile dermatomyositis
10003816

Registration Number: NL-OMON39178

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 30

Inclusion Criteria

- Diagnosed Juvenile Dermatomyositis by a pediatric rheumatologist using the Bohan
and Peter Criteria.
- Be able to follow instructions regarding testing
- Parental and child informed consent
- Age between 8-20 years of age

Exclusion Criteria

- Insufficient understanding of the Dutch language in both children and parents
- Medical events that might intervene with the outcome of testing
- Medical status that will not allow maximal exercise testing (e.g. acute fever, heart
conditions)

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are:<br /><br>• Exercise capacity during a graded exercise test with respiratory gas analysis<br /><br>• Muscle strength as assessed with hand-held dynamometry<br /><br>• Fatigue as assessed with the PEDSQL fatigue scale</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• Muscle soreness as assessed with the 10 cm Visual Analogue Scale<br /><br>• Muscle function as assessed with the Childhood Myositis Assessment Scale<br /><br>(CMAS)<br /><br>• Walking distance at the 6-minutes walking test<br /><br>• Quality of life as assessed with the PEDSQL questionnaire<br /><br>• Functional ability as assessed with the Childhood Health Assessment<br /><br>Questionnaire<br /><br>• Physical activity as assessed by 7 days activity monitoring using an Actical<br /><br>accelerometer<br /><br>• Physical activity enjoyment as assessed with the Physical Activity Enjoyment<br /><br>Scale<br /><br>• Muscle strength as assessed with the Bruininks-Oseretsky Test of Motor<br /><br>Proficiency 2 Subscale 8 - Strength</p><br>