Muscle Synergies After Stroke

Completed

• Conditions: Stroke

• Registration Number: NCT03731299
• Lead Sponsor: Universiteit Antwerpen

Brief Summary

The aim of this systematic review was to determine the number of muscle synergies and the distribution of muscle weightings in stroke patients during gait.

Detailed Description

The aim of this systematic review was to determine the number of muscle synergies and the distribution of muscle weightings in stroke patients during gait. Although literature has suggested that merging of synergies occurs after stroke and that a larger number of is associated with increased motor function if compared with healthy adults. IIt is still unknown if this hypothesis is also relevant when comparing different functional levels within a stroke population and what functional impact of altered synergies on walking behavior is.

Study Timeline

• Study Start: 2015-04-01
• Primary Completion: 2017-07-01
• Study Completion: 2017-12-01
• Study First Submitted: 2018-10-26
• Status Verified: 2018-11
• Study First Submitted QC: 2018-11-05
• Last Update Submitted: 2018-11-05
• Study First Posted: 2018-11-06
• Last Update Posted: 2018-11-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 114

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amount of muscle synergies derived by non-negative matrix factorization	Once, in the week of inclusion	Spatial characteristic of muscle synergy compared to healthy adults: the amount of synergies during walking in stroke subjects, the amount of muscles in one synergie and which muscles in one synergy

Secondary Outcome Measures

Name	Time	Method
Distribution of muscle synerigies derived by non-negative matrix factorization	Once, in the week of inclusion	Temporal characteristic of muscle synergy compared to healthy adults: When are these synergies active during the gait cycle (100%).