Validation of Advanced Physiological MR Imaging Biomarkers

Recruiting

• Conditions: Brain tumour; Glioma; 10027655

• Registration Number: NL-OMON55199
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

- Individuals of 18 years or older
- Referred for surgery for resection or biopsy of brain tumour, including
meningioma and glioma patients.
- Referred for surgery for resection or biopsy of brain metastasis.
- Written informed consent conform ICH-GCP

Exclusion Criteria

- Contra-indication for MRI (implanted metal parts, e.g. stents, vascular
clips, pacemakers)
- Inability to give consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The correlation of advanced MRI biomarkers with proteomics or histopathological<br /><br>measurements of targeted biopsies in glioma.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Overall Survival (OS) and progression free survival (PFS).</p><br>