An Evaluation of the Effectiveness of Ibuprofen and Morphine for Acute Pain in Sickle Cell Disease - Ibuprofen and Morphine for Acute Sickle Cell Pai
- Conditions
- Sickle Cell Disease
- Registration Number
- EUCTR2008-006846-24-GB
- Lead Sponsor
- orth West London Hospitals NHS Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 320
Adult patients with SCD of any phenotype and gender aged 16 years and over
Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
1. Patient has a history of allergic reaction to either morphine or ibuprofen
2. Patient has contraindications to morphine or ibuprofen, e.g. peptic ulcer disease, NSAID-induced asthma
3. Patient in a drug dependency programme
4. Patient is on renal dialysis
5. Stroke within the last 6 weeks
6. Platelet count < 50 X 10E9/l
7. Patient is pregnant or breastfeeding
8. Doctor unwilling to randomise the patient for other reasons
9. Previous participation in the trial
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method