Evaluation of the Ovarian Reserve in Patients Who Hypogastric Arteries and or Uterine Arteries Had Been Ligated

Not Applicable

• Conditions: Uterine Artery Ligation; Hypogastric Artery Ligation; Ovarian Reserve
• Interventions: Procedure: Hypogastric and/or uterine artery ligation

• Registration Number: NCT02995343
• Lead Sponsor: Ege University

Brief Summary

Patients who hypogastric arteries and/or uterine arteries had been ligated will be evaluated in terms of ovarian reserve markers such as anti-mullerian hormone levels, ovarian volumes, antral follicule count, follicule stimuli hormone and estrogen levels. Investigators will search their archives for finding suitable patients for study. Investigators will especially notice being at least 6 month time of interval between surgery and evaluation time. Ultrasound examination and taking blood sample will be performed on 2nd or 3th day of menstrual cycle. These results will be compared with normal postpartum women's results. It will be evaluated that there is or not any effect of the hypogastric arteries and/or uterine arteries on ovarian reserve

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11
• Study First Submitted: 2016-12-12
• Study First Submitted QC: 2016-12-13
• Study First Posted: 2016-12-16
• Status Verified: 2019-03
• Last Update Submitted: 2019-03-26
• Last Update Posted: 2019-03-28
• Primary Completion: 2019-08
• Study Completion: 2019-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• Patients had been ligated hypogastric and/or uterine arteries
• Patients are in 6 month period after surgery
• Without performed hysterectomy
• No older than 40 years old
• No history about endocrinopathy which have an effect upon ovarian reserve

Exclusion Criteria

• Patients had been made other gynecologic surgery such as fallopian tube ligation and hysterectomy etc.
• Patients are older than 40 years old
• Patients use drugs which have an effect upon ovarian reserve
• Patients have diseases which have an effect upon ovarian reserve such as some endocrinopathy, malign diseases which require radiotherapy and chemotherapy etc.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Hypogastric and/or uterine artery ligation	Hypogastric and/or uterine artery ligation	Patients who had been ligated hypogastric artery and or uterine artery for ceasing uterine bleeding during c-section

Primary Outcome Measures

Name	Time	Method
Anti-mullerian hormone levels will be evaluated	6 months after surgery and delivery
Estrogen levels will be evaluated	6 months after surgery and delivery
Antral Follicule Count will be evaluated	6 months after surgery and delivery
Ovarian volume will be evaluated	6 months after surgery and delivery
Follicule Stimuli Hormone levels will be evaluated	6 months after surgery and delivery

Trial Locations

Locations (1)

Ege University, Medicine Faculty, Department of Obstetrics and Gynecology; 🇹🇷 Izmir, Turkey