To study the prevalence of diabetes in an individual specific body type i.e Prakriti through genetic study
- Conditions
- Health Condition 1: E08-E13- Diabetes mellitus
- Registration Number
- CTRI/2019/05/019029
- Lead Sponsor
- Ministry of AYUSH govt of India
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Volunteer willing to include them in the study by signing in the informed consent (Annexure-3)
Either sex
Age: 30 years and above
Freshly diagnosed cases of diabetes
Pre-diabetics
Chronic cases with or without complications
Patients on Allopathic medicines
Patients on Ayurvedic / Alternative (diet, lifestyle, drug, procedure, yoga) treatment
Patients taking combination treatment
Volunteer unwilling to include themselves in the study by signing in the informed consent
Secondary diabetes
Age below 30 years
Hypothyroidism
Pregnancy/lactation
Major co-morbidities like (known / Clinically diagnosed) cases of Cancer, CVA, HIV/AIDS, TB, Acute infection, any other conditions which investigator feels will jeopardize the study
Immuno compromised patients
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence/frequency of different Prakriti individuals in diabetes. <br/ ><br>Correlation between Madhumeha and Prakriti lakshanas with elucidation of specific endophenotype of the disease. <br/ ><br>Correlation of madhumeha endophenotypes with markers of disease progression <br/ ><br>Development of repository of Diabetes type II samples like DNA Serum & Plasma <br/ ><br>Timepoint: 3 years
- Secondary Outcome Measures
Name Time Method Correlation of madhumeha endophenotypes with molecular signatures (biochemical, genomic SNP, and gut microbial) associated with Prakriti types <br/ ><br>â?¢Correlation of madhumeha endophenotypes with markers of t2DM disease suceptibilityand progression <br/ ><br>Timepoint: 3 years