Effect van fosfaat verlaging op FGF23 en bloedvaten.Effect of phosphate reduction on FGF23 and bloodvessel function.
Recruiting
- Registration Number
- NL-OMON25966
- Lead Sponsor
- Vrije Universiteit Medisch Centrum (VUmc) Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
1. Patients with eGFR 30-60 ml/min/1,73 m2;
2. Serum phosphorus level <1,49 mmol/L and >1,0 mmol/L;
Exclusion Criteria
1. Known allergy or intolerance for sevelamer-containing drugs;
2. Patients with heart failure;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum FGF23 and phosphaturia before and after 8 weeks of treatment with sevelamer-carbonate.
- Secondary Outcome Measures
Name Time Method Pulse Wave Velocity measured before and after the treatment with Sevelamer.