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Efficacy and safety of PANtoprazole in the treatment and SympTom relief in patients with gAstRoesophageal reflux disease (GERD) – PAN-STAR

Conditions
gastroesophageal reflux disease (GERD)
MedDRA version: 12.1Level: LLTClassification code 10066874Term: Gastroesophageal reflux disease
Registration Number
EUCTR2009-017229-20-PL
Lead Sponsor
KRKA-POLSKA Sp. z o.o.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

– Patients of both genders at the age over 18
– Patients with typical GERD symptoms (heartburn/or regurgitation)
– Signed informed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

– Patients with esophageal or gastric malignancies
– Patients with a terminal condition
– Patients with renal impairment (serum creatinine > 300 µmol/l)
– Pregnancy and breast-feeding
– Patients positive for Helicobacter pylori infection
– Patients with GERD symptoms who have been unsuccessfully treated with proton pump inhibitors during a period of 6 months prior to inclusion
– Patients with Barretts’ esophagus
– Patients with evidence of dysplasia
– Patients with active ulcer disease (gastric, duodenal)
– Patients who have been treated with a proton pump inhibitor 30 days or less prior to the first visit
– Hypersensitivity to pantoprazole
– Patients taking any medicine that should influence the results of the treatment
– Patients not able out of any reason to make decisions about participation in the study or not able to fulfill the requirements of the protocol

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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