ICU-acquired Weakness in Extracorporeal Membrane Oxygenation Support: Frequency and Risk Factors

Second Affiliated Hospital, School of Medicine, Zhejiang University1 site in 1 country85 target enrollmentMarch 1, 2017

ConditionsICU Acquired Weakness

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: ICU Acquired Weakness
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Enrollment: 85
Locations: 1
Primary Endpoint: Differences between ICU-acquired weakness in patients receiving extracorporeal membrane oxygenation support
Last Updated: 4 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

We conducted a retrospective study of critical ill patients who used ECMO during their ICU stay. ICU-AW was diagnosed at the time when patients discharged and had a Medical Research Council (MRC) sum score < 48 out of a maximal score of 60. We divided patients to ICU-acquired weakness group and no ICU-acquired weakness group and compared their clinical characteristics. Baseline characteristics and therapy details were collected from the case report forms and inspection reports. Univariable analysis and logistic regression analysis were used to analyze clinical characteristics of individuals and to find risk factors of ICU-AW.

Registry

clinicaltrials.gov

Start Date

March 1, 2017

End Date

June 1, 2022

Last Updated

4 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Critical ill patients who used extracorporeal membrane oxygenation during their ICU stay. Patients were recruited from the general ICU of the second affiliated hospital of Zhejiang University, between March 2017 to March 2020.

Exclusion Criteria

•Patients who was less than 18 years old, had been proven or suspected neurological impairment, using extracorporeal membrane oxygenation less than 24 hours, severe head or spinal cord injury and pregnant woman.

Outcomes

Primary Outcomes

Differences between ICU-acquired weakness in patients receiving extracorporeal membrane oxygenation support

Time Frame: 1 day

We compared the clinical characteristics between ICU-acquired weakness group and no ICU-acquired weakness group by univariate analysis . Then we used logistic regression analysis and found out differences of ICU-acquired weakness.