HIF-1 Alpha, VEGF and MMP-8 Levels in PICF of Smokers Versus Non Smokers
Completed
- Conditions
- Peri-Implantitis
- Registration Number
- NCT05325918
- Lead Sponsor
- Future University in Egypt
- Brief Summary
Smoking is a major risk factor for developing peri-implantitis so the current study is comparing inflammatory markers in smokers versus non smokers to know if they have a potential role in pathogenesis of peri-implantitis
- Detailed Description
Peri -implant crevicular fluid was obtained from seven smoker patients and then compared to peri-implant crevicular fluid from seven non smoker individuals.
The peri-implant crevicular fluid was obtained using periopaper strips then analyzed using ELISA kits of these markers; HIF-1 Alpha, VEGF and MMP-8
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 14
Inclusion Criteria
- Medically free patients
- Individuals with restored implants placed one year or more before study enrollment
- Both genders
- Age range 20-50 years old
Exclusion Criteria
- Pregnant Females
- Lactating females
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of levels of HIF-1 Alpha, VEGF and MMP-8 in peri-implant crevicular fluid Baseline Markers collected using periopaper strips
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of oral and dental medicine,FUE, Cairo,Egypt
🇪🇬Cairo, Egypt