Evaluation of the effect of botulinum toxin and Profhilo hyaluronic acid injection in rejuvenation of the neck.
Phase 2
- Conditions
- Horizontal neck lines.
- Registration Number
- IRCT20201204049589N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Adults over 18 years and under 70 years
Signing a voluntary agreement
WSRS (Wrinkle Severity Rating Scale) between 4 - 2
They do not want to have a surgical procedure
Patients who are not candidates for surgery
Exclusion Criteria
Pregnancy and breastfeeding
Neuromuscular diseases such as myasthenia gravis•
Hypersensitivity to Botox or human albumin•
Uncontrolled systemic disease
Infection, scarring, abnormality at the injection site
History of Botox injection or lower face filler in the last 12 months
Patients treated with aspirin, immunosuppressants, narcotics, antiDepressants and corticosteroids in the last 3 months
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Wrinkle severity rating scale (WSRS). Timepoint: The first visit and 6 months after Dysport injection and the second time filler. Method of measurement: Score based on the severity of wrinkles by comparing photography and dermoscopy before and after treatment.
- Secondary Outcome Measures
Name Time Method