Effect of simvastatin gel on periodontitis
Not Applicable
- Conditions
- Furcation involvement class 2 mandible molars (periodontitis).Periodontal disease, unspecified
- Registration Number
- IRCT2016112631116N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
1- presence at least 1 pair of first or second molar of mandible bilaterally accompanied with fraction involvement class 2 with less or equal 3 mm horizontal penetration of probe. 2- presence at least 2 mm keratinized gingiva around each tooth.
Exclusion criteria: 1- smoking. 2- history of systemic disease. 3- pregnant or breast feeders. 4- history of antibiotic consumption within 2 months. 5- hx of periodontal treatment within 6 months. 6- hx of hypersensitivity to statins. 7- pt with statin treatments. 8- aggressive periodontitis. 9- tooth mobility grade 3. 10- pulp-pathology and incomplete RCT or PA lesion. 11- poor oral hygiene.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical Attachment Level. Timepoint: preoperative, during and 6 months post surgery. Method of measurement: probe and CBCT.
- Secondary Outcome Measures
Name Time Method Recession. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe.;Bone Fill. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe and CBCT.;Probing pocket depth. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe and CBCT.;Horizontal penetration in the Furca. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe and CBCT.;Bleeding Index. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe.;Plaque Index. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe.