Investigating the effect of optimising amino acid intake on obesity rates in individuals aged 65-80 years.

Not Applicable

Recruiting

• Conditions: Obesity; Diet and Nutrition - Obesity

• Registration Number: ACTRN12621000402842
• Lead Sponsor: The University of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-04-12
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

Females (post-menopausal) or males, 65-80 years, BMI 20-35kg/m2 will be recruited

Exclusion Criteria

Exclusion criteria will include diabetes mellitus (insulin dependent, Type 1 or 2), renal or liver disease, cancer or active neoplasms, hyperthyroidism (unless treated or under control), schizophrenia, sleep apnea, taking medications known to affect weight or energy expenditure, antibiotics use in the previous four weeks, unintentional weight loss (>10% body weight) over the past 5 years, smoking, alcohol intake >3 standard drinks/day or unwilling to refrain from alcohol, vegan and vegetarians, food allergies and/or intolerances, and when changes in diet are contraindicated by treating doctor.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Objective/quantitative appetite assessed by plasma FGF21 and grehlin.[Baseline and four-week post intervention commencement.];Subjective/qualitative appetite assessed by participant self-report (assessed by appetite questionnaire).[Baseline and four-week post intervention commencement.];Subjective/qualitative energy intake assessed by participant self-report (weighed food record)[Baseline and four-week post intervention commencement.]