Nasal Intermittent Positive-Pressure Ventilation vs Nasal Continuous Positive Airway Pressure for Twin Infants With Respiratory Distress Syndrome

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University1 site in 1 country286 target enrollmentJuly 1, 2012

ConditionsNeonatal Respiratory Distress Syndrome

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Neonatal Respiratory Distress Syndrome
Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Enrollment: 286
Locations: 1
Primary Endpoint: incidence of intubation
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In the present study, we hypothesized that primary mode nIPPV initiated shortly after birth would decrease the incidence of intubation or death in twin infants when compared to nCPAP.

Detailed Description

After inclusion of eligible twins infants,one of the twins was supported by nCPAP and another nIPPV.

Registry

clinicaltrials.gov

Start Date

July 1, 2012

End Date

July 30, 2017

Last Updated

8 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Responsible Party

Principal Investigator

Chen Long,MD

Prof;MD

Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Eligibility Criteria

Inclusion Criteria

•Clinical diagnosis of mild-moderate respiratory distress syndrome
•requiring a fraction of inspired oxigen (FiO2 ) \<0.40 to keep oxygen saturation of 90%-95%
•a chest X-ray suggestive of early stage hyaline membrane disease, (i.e. mild microgranulia and air bronchogram)