EUCTR2007-000260-24-IT进行中（未招募）不适用
EVALUATION OF THE CLINICAL AND MICROBIOLOGICAL EFFICACY OF N-ACETILCISTEINA 600 MG, IN COMBINATION TO CEFPODOXIMA PROXETILE, IN THE THERAPY OF THE INFECTIONS OF THE HIGH RESPIRATORY WAYS IN ADULT PATIENTS CLINICAL STUDY MULTICENTRIC, TO GROUPS PARALLELS, DOUBLE - BLIND VS PLACEBO - ND
ZAMBON ITALIA0 个研究点开始时间: 2007年7月4日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Patients will be included in the study males and females, of age comprised between the 18 and 75 years, affections from recurrent acute infections or subacute/of the high respiratory ways rinosinusitis, faringotonsillitis, infections of the medium ear , to probable bacterial aetiology. The clinical diagnosis, may to be confirmed afterward from the microbiological medical report, based on the isolation, the identification and the test of sensibility of the pathogenic one to cefpodoxima antibiogramme . Waiting for turned out of laboratory, the decision to include equally the patient comes remitted to the responsability of the single clinical Experimenter. In this case the patient, treaty empirically, would like afterward excluded from the primary analysis of effectivity in case she turns out you of the tests microbiological were denied infection to you to aetiology turns them or insensibility of the bacteria she isolates you to the treatment with cefpodoxime .
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Hypersensitivity to drugs in study or other antibiotics beta-lattamici or one whichever of excipients - Previous anaphylactic reactions or other serious reactions to other antibiotics beta-lattamici - serious Pathologies like the respiratory clogging or a faringeo abscess, whose main symptoms are intense disfagia, impossibility to swallow also it salted it, fever much elevating, dyspnoea, respiratory stridore - Assessed fenilchetonuria - Suspects infection from Pseudomonas - Asthma like main primitiva affection/ - allergic Rhinitis - Assessed batteremia, meningitis or infection of the next woven ones to the paranasals breasts - Assessed immunodeficiency neutropenia, on counts of neutrophil 1000 mm3 - Women in state of assessed or presumed pregnancy, in breast-feeding and those in age fertile that, in the period of observation, do not adopt an effective contraceptive system estroprogestinici, I.U.D., condom, spermicidal diaphragm with cream, etc - Patients with clearance ofthe creatinine 40 ml/minute. The clearance of the creatinine it will be estimated from the values of the creatinine in the serum, using the formula of Cockcroft and Gault paragraph 8,5 - Patients who had assumed antibiotic in the 5 previous days enlistment in the study - Patients enlists in other clinical experimentations in the three previous months enlistment to you in the study - Patients with pathologies or therapies that can interfere with the appraisal of the treatments in study - Necessity of different an antibiotic therapy from those specified in the study - Patients who, to judgment of the Experimenter, introduce other conditions that they can interfere with the compliance to the treatment and/or the previewed procedures and therefore with the corrected execution of the study - Pathologies that, to judgment of the Experimenter, could not benefit from some of the therapies proposed from the study protocol.
研究者
相似试验
尚未招募
2 期
Clinical and microbiological effectiveness of herbal gum astringent after scaling in gingivitis patientsCTRI/2022/04/041627Purexa Global Pvt Ltd
尚未招募
2 期
Checking clinical effects of scaling and root planing with antibiotics and lasers in treatment of gum diseaseCTRI/2020/11/029010DR GULAFSHA M
招募中
2 期
Studying the effect of addition of carboplatin and gemcitabine to standard therapy in improving response rate in breast cancer patientsBreast cancer.Malignant neoplasm of breastIRCT2017100136491N1Ministry of Research, Shiraz University of Medical Sciences, Pharmaceutical Sciences Research Center50
已完成
3 期
Clinical and bacteriological Effects of Synbiotic as an Adjunct in Phase I Periodontal TherapyChronic periodontitis.Chronic periodontitisK05.3IRCT20130216012487N7Esfahan University of Medical Sciences28
已完成
不适用
Investigation of the clinical significances and the pathological features of the lanthanum deposition at the gastric mucosapatients on hemodialysisJPRN-UMIN000038929Osaka medical college42