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临床试验/NCT07298798
NCT07298798进行中(未招募)不适用

Comparison of the Closed Kinetic Chain and Isometric Exercise in Female Patient With Patellofemoral Pain Syndrome Associated With Knee Osteoarthritis: A Randomized Control Trial

Dow University of Health Sciences1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2023年11月9日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
70
试验地点
1
主要终点
numerical pain rating scale (NPRS)

研究概览

简要总结

Investigator study aims to compare the benefits of isometric exercise and closed kinetic chain exercises in strengthening programs to lessen pain along with enhance functionality in patients with PFP that are being associated with osteoarthritis and the assessment of PFP pertains to its recognition and the determination of significant therapeutic techniques. 70 Participants from the department of physiotherapy, Civil Hospital Karachi CHK and Dow University of Health Science (DIPMR) will be randomly assigned into two groups, an experimental group receiving closed kinetic chain exercise, and a control group receiving isometric exercises. The therapy will last four weeks, consisting of twelfth sessions. There will be 35 to 40 minutes in each session, Patients will be evaluated on primary outcome measure, pain intensity and functional limitation using various scales, including the numerical pain rating scale (NPRS) and Kujala/anterior knee pain scale (AKPS)

详细描述

The most prevalent issue of musculoskeletal knee joint that impact is patellofemoral pain syndrome (PFPS) particularly in young adults and the elderly, causing severe discomfort behind and around the patella, making it the primary etiology for anterior knee discomfort. Patellofemoral joint may be the first compartment affected in early knee osteoarthritis. Most exercise programs designed for treating p a t e l l o f e m o r a l p a i n ( PFP) focus on strengthening the quadriceps, primarily the vastus medialis oblique (VMO). A rehabilitation program including closed kinetic chain exercises and isometric exercises may be beneficial for patients with patellofemoral pain (PFP) to improve their functional limitations and minimize pain. Closed kinetic chain exercises improve functional movement patterns, while isometric exercises are better tolerated during pain or inflammation. The effectiveness of these approaches in individuals with patellofemoral pain (PFP) associated with knee OA is unclear, but understanding their differential impacts can guide targeted rehabilitation strategies for this complex patient population. Investigator aims to compare the benefits of isometric exercise and closed kinetic chain exercises in strengthening programs to lessen pain along with enhance functionality in patients with PFP that are being associated with osteoarthritis, Participants from the department of physiotherapy, Civil Hospital Karachi CHK and Dow University of Health Science (DIPMR) will be randomly assigned into two groups, an experimental group receiving closed kinetic chain exercise, and a control group receiving isometric exercises. The therapy will last four weeks, consisting of twelfth sessions. There will be 35 to 40 minutes in each session, Patients will be evaluated on pain intensity and functional limitation using various scales, including the numerical pain rating scale (NPRS) and Kujala/anterior knee pain scale (AKPS).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
35 Years 至 60 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Age between (35 to 60) years.
  • Gender: female.
  • The numerical pain rating scale (NPRS) is greater than three out often i.e. 3/10 score.
  • Patient experiences anterior knee pain due to such activities like squatting, prolonged sitting, running and stair climbing.
  • Patient with unilateral or bilateral knee pain with positive radiographic imaging.
  • Patients have grade 1 and 2 knee osteoarthritis (K&L classification).

排除标准

  • Any past record of knee surgery.
  • Any past record of knee fracture.
  • Patients with any neurological disorder.
  • Cancer, malignancy or any bone tumor.
  • Comorbid like diabetes mellitus.
  • Any systemic inflammatory arthritis.

研究组 & 干预措施

GroupA . given treatment closed kinetic chain exercise

Experimental

Terminal knee extension, The patient stand facing the plinth with feet shoulder-width apart and a theraband looped around their knee and other plinth legs. patient bend their knees to a 30-degree angle, extend their leg against the band's resistance, and hold this position for six seconds.

VMO squat, The position of patient, hip and knee will bend, weight of the body on feet and feet about shoulder width apart and turn the feet outward about 45 degrees and position hold for 30 second.

干预措施: Terminal knee extension. .VMO squat. [TheraBand] (Behavioral)

GroupB . given treatment isometric exercise SLR, Static quads.

Experimental

Static Quads The patient is long sitting or supine on their back, with a foam roll or towel behind their knee. Contract your quadriceps muscles while pressing down on the towel, maintaining this position for five seconds.

Straight leg raising (SLR) The patient will be laying in supine, and before the exercise's lifting phase, a maximal isometric quadriceps contraction will be executed, followed by raising the leg to a height of 10cm above the plinth for 10 seconds.

干预措施: Isometric exercises [knee roller] (Behavioral)

结局指标

主要结局

numerical pain rating scale (NPRS)

时间窗: 12th sessions for four weeks ,outcome measures will take place both, at the baseline when intervention start and four weeks, following the intervention

1\. Numerical pain rating scale (NPRS) Pain intensity will measure using NPR scale (no need for permission), a reliable instrument retest reliability of 0.95 , 0 represents no pain and 10 represents severe suffering. 10= indicate worse pain 5= indicate moderate pain 0 = indicate no pain.

. Kujala/ Anterior knee pain scale (AKPS)

时间窗: 12th sessions for four weeks, ,outcome measures will take place both, at the baseline when intervention start and four weeks, following the intervention

we will use the Kujala scale to measure functional limitations, a reliable instrument retest reliability of 0.9 in patient with PFPS, total 13 self-reported questionnaire. AKPS graded 0 to 100, 100 being the highest possible score with no pain and disability. Lower scores reflect greater pain and disability.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

FAKHRA ASGHAR

Principal Investigator

Dow University of Health Sciences

研究点 (1)

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