Comparison of pregnancy rate in single versus double Intrauterine Insemination (IUI) when polycystic ovarian syndrome or unexplained, mild male factor infertility is present.
Phase 3
- Conditions
- Ovarian dysfunction.Polycystic ovarian syndrome
- Registration Number
- IRCT201307231306N7
- Lead Sponsor
- Vice Chancellor for Research, Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 580
Inclusion Criteria
base serum level of FSH<12 mIu/l; females with polycystic ovarian syndrome who have not become pregnant despite six times of ovulation induction and having a suitable ovum.Females whose male partners have unexplained, mild male factor infertility; have no severe medical illness; no obstruction in tubes; no uterine anomaly.
Exclusion criteria: existence of less than 2 or more than 5 ovarian follicles; any severe medical illness; females with ovarian cysts greater than 15mm after 3rd day following menstruation (diagnosed using transvaginal sonography).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pregnancy. Timepoint: 14 days after IUI. Method of measurement: Serum BHCG level assessment.
- Secondary Outcome Measures
Name Time Method Pregnancy outcome. Timepoint: 14 days after IUI. Method of measurement: Serum BHCG level assessment.;Diagnosis of intrauterine pregnancy. Timepoint: 7th week of pregnancy. Method of measurement: Fetal Heart Rate (FHR) (transvaginal sonography).;Frequency of complications (abortion, ectopic pregnancy, multifetal gestation). Timepoint: Completion of treatment and follow up period. Method of measurement: Diagnosis of ectopic pregnancy and.