IRCT20230823059238N2招募中3 期
Investigating the effect of melatonin combined with betamethasone mouthwash compared to betamethasone mouthwash alone in the treatment of ulcerative oral lichen planus
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 32
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 70 years（—）
- 性别
- All
入选标准
- •Definitive diagnosis of ulcerative oral lichen planus based on clinical findings: white and red components with different designs, presence of reticular or papular tissue with erogenous lesions and histopathological criteria: 1) hyperparakeratosis or hyperorthokeratosis areas, often with thickening of the granular cell layer and a saw-tooth appearance in Rat pegs 2) Condensed degeneration or necrosis in the basal cell layer 3) An eosinophilic band that may be seen just below the basement membrane and contains fibrin covering the lamina propria. 4) Dense subepithelial band-like infiltration of lymphocytes and macrophages 5- Presence Ulcer or fibrinopurulent membrane
- •Patients with complete records including demographic and clinical information
- •Patients without underlying disease
- •People who have the ability to give informed consent and do not need a legal representative.
排除标准
- •pregnant women
- •People with underlying disease
- •Any treatment that has been done for these injuries
- •Use of immunosuppressive drugs
- •Incomplete file
- •The patient's unwillingness to participate in the research
研究者
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