Prevalence of Eosinophilic Esophagitis in Children With Celiac Disease and Prevalence of Celiac Disease in Children With Eosinophilic Esophagitis in a Tertiary Community Hospital
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 56
- 主要终点
- Review of histopathology reports of esophageal biopsies to record the number of eosinophils per high power field.
研究概览
简要总结
Celiac disease (CD) and eosinophilic esophagitis (EE) are distinct diseases of the gastrointestinal tract with specific clinico-pathological characteristics. In recent years, in the literature, several children who underwent upper gastrointestinal endoscopy for suspected CD, which was confirmed histologically, were also found to have coexistent EE. There are reports of coexistent CD and EE. We would like to see the prevalence of EE in children with CD and the prevalence of CD in children with EE in our population, and to do so would like to review medical records. Our objectives are to determine if children with celiac disease have a high prevalence of eosinophilic esophagitis.and to determine if children with eosinophilic esophagitis have increased risk of developing celiac disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 2 Years 至 21 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Seen in the Pediatric Gastroenterology clinic at St. John Hospital & Medical Center during study time frame
- •Age 2-21 years old
- •Diagnosed with CD or EE or both based on the endoscopic and histopathological findings .
排除标准
- •Gastroesophageal reflux diagnosed by PH probe.
- •History of chemical ingestion
结局指标
主要结局
Review of histopathology reports of esophageal biopsies to record the number of eosinophils per high power field.
时间窗: Retrospective chart review study, no contact made with patients, so no patient time is required, expected average of 2 years
次要结局
未报告次要终点
研究者
Hernando Lyons, MD
tSection Chief of Pediatric Gastroenterology at St. John Hospital and Medical Center
St. John Health System, Michigan