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CCI-779 in Treating Patients With Metastatic Melanoma

Phase 2
Completed
Conditions
Melanoma (Skin)
Registration Number
NCT00022464
Lead Sponsor
City of Hope Medical Center
Brief Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.

PURPOSE: Phase II trial to study the effectiveness of CCI-779 in treating patients who have metastatic melanoma.

Detailed Description

OBJECTIVES:

* Determine the anti-tumor activity of CCI-779, in terms of progression-free survival, in patients with metastatic melanoma.

* Determine the toxic effects of this regimen in these patients.

OUTLINE: This is a multicenter study.

Patients receive CCI-779 IV over 30 minutes on day 1. Courses repeat every 7 days in the absence of disease progression or unacceptable toxicity.

Patients are followed for survival.

PROJECTED ACCRUAL: Approximately 40-50 patients will be accrued for this study within 12 months.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (21)

City of Hope Comprehensive Cancer Center

🇺🇸

Duarte, California, United States

USC/Norris Comprehensive Cancer Center and Hospital

🇺🇸

Los Angeles, California, United States

City of Hope Medical Group

🇺🇸

Pasadena, California, United States

University of California Davis Cancer Center

🇺🇸

Sacramento, California, United States

University of Chicago Cancer Research Center

🇺🇸

Chicago, Illinois, United States

Louis A. Weiss Memorial Hospital

🇺🇸

Chicago, Illinois, United States

Decatur Memorial Hospital Cancer Care Institute

🇺🇸

Decatur, Illinois, United States

Evanston Northwestern Health Care - Evanston Hospital

🇺🇸

Evanston, Illinois, United States

Ingalls Memorial Hospital

🇺🇸

Harvey, Illinois, United States

LaGrange Memorial Hospital

🇺🇸

LaGrange, Illinois, United States

Scroll for more (11 remaining)
City of Hope Comprehensive Cancer Center
🇺🇸Duarte, California, United States

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