CCI-779 in Treating Patients With Metastatic Melanoma
- Conditions
- Melanoma (Skin)
- Registration Number
- NCT00022464
- Lead Sponsor
- City of Hope Medical Center
- Brief Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of CCI-779 in treating patients who have metastatic melanoma.
- Detailed Description
OBJECTIVES:
* Determine the anti-tumor activity of CCI-779, in terms of progression-free survival, in patients with metastatic melanoma.
* Determine the toxic effects of this regimen in these patients.
OUTLINE: This is a multicenter study.
Patients receive CCI-779 IV over 30 minutes on day 1. Courses repeat every 7 days in the absence of disease progression or unacceptable toxicity.
Patients are followed for survival.
PROJECTED ACCRUAL: Approximately 40-50 patients will be accrued for this study within 12 months.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (21)
Weill Medical College of Cornell University
🇺🇸New York, New York, United States
LaGrange Memorial Hospital
🇺🇸LaGrange, Illinois, United States
Cancer Care Ontario-London Regional Cancer Centre
🇨🇦London, Ontario, Canada
City of Hope Comprehensive Cancer Center
🇺🇸Duarte, California, United States
City of Hope Medical Group
🇺🇸Pasadena, California, United States
Central Illinois Hematology Oncology Center
🇺🇸Springfield, Illinois, United States
Ingalls Memorial Hospital
🇺🇸Harvey, Illinois, United States
Cancer Care Ontario-Hamilton Regional Cancer Centre
🇨🇦Hamilton, Ontario, Canada
University of Chicago Cancer Research Center
🇺🇸Chicago, Illinois, United States
Louis A. Weiss Memorial Hospital
🇺🇸Chicago, Illinois, United States
Decatur Memorial Hospital Cancer Care Institute
🇺🇸Decatur, Illinois, United States
Fort Wayne Medical Oncology and Hematology, Incorporated
🇺🇸Fort Wayne, Indiana, United States
Evanston Northwestern Health Care - Evanston Hospital
🇺🇸Evanston, Illinois, United States
Abramson Cancer Center of the University of Pennsylvania
🇺🇸Philadelphia, Pennsylvania, United States
Princess Margaret Hospital
🇨🇦Toronto, Ontario, Canada
CCOP - Northern Indiana CR Consortium
🇺🇸South Bend, Indiana, United States
North Shore University Hospital
🇺🇸Manhasset, New York, United States
USC/Norris Comprehensive Cancer Center and Hospital
🇺🇸Los Angeles, California, United States
Oncology/Hematology Associates of Central Illinois, P.C.
🇺🇸Peoria, Illinois, United States
Loyola University Medical Center
🇺🇸Maywood, Illinois, United States
University of California Davis Cancer Center
🇺🇸Sacramento, California, United States