Comparison of Postoperative Analgesic Effects of Transversus Abdominis Plane Block and Quadratus Lumborum Block Type 2
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Pain Intensity
研究概览
简要总结
This study compares analgesic effectiveness of transversus abdominis plane block and quadratus lumborum block type 2 in open hernia repair surgery. All of the patients will receive routine intravenous analgesic regimen. In addition to that one-third of the patients will receive transversus abdominis plane block, one-third will receive quadratus lumborum block type 2. One-third of the patients will not receive any blocks and will constitute the control group
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are over 18 years of age
- •Patients who are scheduled for elective unilateral open hernia repair with tension free mesh techniques
- •Patients who are in ASA's physical status score group 1 or 2
排除标准
- •Patients who are younger than 18 years of age
- •Patients who have severe stenotic heart diseases
- •Patients who have bleeding diathesis
- •Patients who have true allergies to local anesthetics
- •Patients who have neurologic deficits corresponding to effect site of the anesthetic techniques
研究组 & 干预措施
TAP
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Acetaminophen (Drug)
TAP
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: 0.25% Bupivacaine (Drug)
TAP
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: 0.5% Bupivacaine+Glucose (Drug)
TAP
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Tramadol HCl (Drug)
TAP
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive transversus abdominis plane block with 20 ml of 0.25% bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Inguinal Hernia Repair (Procedure)
QLB2
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Acetaminophen (Drug)
QLB2
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: 0.5% Bupivacaine+Glucose (Drug)
QLB2
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Tramadol HCl (Drug)
QLB2
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Inguinal Hernia Repair (Procedure)
QLB2
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive quadratus lumborum type 2 block with 20 ml of %0.25 bupivacaine preoperatively, in addition to intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: 0.25% Bupivacaine (Drug)
CONT
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Acetaminophen (Drug)
CONT
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: 0.5% Bupivacaine+Glucose (Drug)
CONT
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Tramadol HCl (Drug)
CONT
Patients will undergo inguinal hernia repair under subarachnoid block with 0.5% bupivacaine+glucose.
Patients will receive intravenous acetaminophen 1000mg twice a day for postoperative analgesia.
Tramadol HCl 50mg intramuscular will be provided for salvage analgesia postoperatively.
干预措施: Inguinal Hernia Repair (Procedure)
结局指标
主要结局
Pain Intensity
时间窗: 48 hours after surgery
Postoperative pain intensity according Numeric Rating Scale between 0-10 (0=no pain, 10=worst pain ever
次要结局
未报告次要终点