Comparative Analysis of Risk Factors and Prediction of Frailty Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- frailty prevalence
研究概览
简要总结
Assessing frailty syndrome in elderly patients in Almaty To study the features of the clinical course in the group of patients with a pre-frailty and in the group with frailty syndrome
详细描述
2 cohorts of patients: a group of patients with pre-frailty (300 patients) and a group of patients with frailty syndrome (300 patients).
Comparative analysis of the indicators of two groups (demographic, laboratory indicators, scale results).
To study the features of the clinical course of frailty. To determine the risk factors for the development of frailty. To identify criteria for an unfavorable outcome of frailty.
The study will involve patients over the age of 60. The recruitment of patients will be carried out in polyclinics and nursing homes in Kazakhstan.
The collection of primary information and a comprehensive examination of patients will be based on the following research methods recommended by WHO:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients over 60 years of age
- •Signatories of the informed consent to participate in the study
排除标准
- •Not agreeing to participate in scientific research
- •Elderly people who do not understand the purpose of the study
- •Severe and decompensated diseases that do not allow the study.
- •Concomitant oncological diseases
- •Concomitant neurological and mental disorders that impede the study
结局指标
主要结局
frailty prevalence
时间窗: 1 March 2024 - 31 December 2024
A FRAIL scale or Fried frailty criteria is used (weight loss, exhaustion, low physical activity, slowness, weakness). The participants were divided into three stages: non-frail (score 0), pre-frail (score 1-2) and frail (score 3-5).
次要结局
未报告次要终点
研究者
Indira Omarova
Principal Investigator, Assistant of the department of General Medical Practice
Asfendiyarov Kazakh National Medical University