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Traditional Bed Baths Versus Disposable Wet Wipes

Not Applicable
Completed
Conditions
Intimate Hygiene
Interventions
Device: wet wipes
Device: water and soap
Registration Number
NCT02984527
Lead Sponsor
University of Southern Denmark
Brief Summary

The Purpose of the study is to compare the effectiveness on microbiological counts from skin swaps after wash with water and soap or wet wipes.

Detailed Description

The study is a crossover clinical trial where the effect of two interventions is compared on the same subject.

The two interventions are:

* Intimate hygiene with water and soap

* Intimate hygiene with prepackaged disposable wet wipes

Null hypothesis: Same effectiveness to reduce microbiological counts on skin

Alternative hypothesis: Significant different effectiveness to reduce microbiological counts on skin

Each individual receives the two interventions in random order. The effect of the interventions on microbiological counts on the patients skin is evaluated on the same patient.

A crossover trial requires half the number of participants and reduces confounding factors.

All participants receive a sequence of the two different interventions. But there is a sufficient gab between the two interventions to ensure a washout period and avoid a crossover effect. In this study this is 12-24 hours.

The study uses block randomization, without intra block correlation to achieve allocation balance over time.

Furthermore it may prevent some predictable allocation.

Microbiological sampling with moistened swaps and aseptic techniques, sterile equipment and sterile recovery medium (Stewarts Medium) are used to obtain skin samples from the patients before and after intimate hygiene with water and soap and wet wipes.

Differences in microbiological skin counts will be compared (delta values) before and after the two interventions and between interventions.

Data will be blinded during microbiological count and statistical analyses.

Analyses:

Data are structured in CASTOR and will be stored in a secure Team Collaboration Software Tool (SharePoint).

Descriptive analysis including mean, median, confidence interval, standard deviation, and standard error.

Statistical analyses will be performed using STATA. Test of differences will be performed by simple t- test or Wilcoxon sign rank test, depending on the distribution of the data. A multiple regression analysis including possible confounders will be considered.

Inclusion of 68 patients

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
72
Inclusion Criteria
  • Patients who need intimate hygiene
  • Admitted for minimum two days
  • Understand oral information
  • And apple to sign written consent
Exclusion Criteria
  • Diarrhea
  • Dementia
  • Dying

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
disposable wet wipes first daywet wipesIntimate hygiene performed with wet wipes first day and water and soap second day
disposable wet wipes first daywater and soapIntimate hygiene performed with wet wipes first day and water and soap second day
water and soap first daywet wipesIntimate hygiene performed with water and soap first day and disposable wet wipes second day
water and soap first daywater and soapIntimate hygiene performed with water and soap first day and disposable wet wipes second day
Primary Outcome Measures
NameTimeMethod
microbiological counts on skin before and after interventionstwo consecutive days

microbiological counts from skin swaps before and after washing with water and soap and before and after washing with disposable wipes

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hospital of Southern Jutland

🇩🇰

Aabenraa, Jutland, Denmark

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