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Clinical Trials/NCT03947060
NCT03947060
Completed
N/A

BI-SENSES: Validation of Nasal Versus Frontal Placement of the SedLine® Sensor Through Processed Electroencephalography in Adult Patients Undergoing General Anesthesia

Cleveland Clinic Abu Dhabi1 site in 1 country40 target enrollmentDecember 1, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Depth of Anesthesia Monitoring
Sponsor
Cleveland Clinic Abu Dhabi
Enrollment
40
Locations
1
Primary Endpoint
Validation of nasal SedLine® EEG sensor position for monitoring the depth of anesthesia using processed electroencephalograph values
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

SedLine® Brain Function Monitoring provides real-time insight into a patient's depth of anesthesia with bilateral data acquisition and processing of electroencephalogram (EEG) signals. Four active EEG leads collect data from the frontal lobe with a sensor position on the patient's forehead.

Whenever a frontal approach for neurosurgical procedures is required or the frontal placement of the EEG is not indicated, it would not be possible to place the SedLine® .

Numerous studies have analyzed the change of position and the application of alternative positions for other devices used in assessing the depth of anesthesia. Albeit, yet to date, there is no study that analyzed the application of alternative positions for the SedLine® sensor.

Detailed Description

The purpose of study is to compare the standard forehead placement versus a nasal placement of SedLine® sensor for neuromonitoring. The hypothesis is that placing the central sensors in the montage approximately 2 cm below the standard recommended placement, across the nasal bridge and then running under the eyes to the normal temporal leads placement would put the entire montage out of the operative field and would still have corresponding values and EEG signals. The primary outcome measure is to monitor and compare processed electroencephalograph (EEG) values (PSi- Patient State Index, SEFL- Spectral Edge Frequency Left, SEFR- Spectral Edge Frequency Right, SR-Suppression Ratio, EMG-Electromyography, ARTF-Artifact) and EEG waveforms, on both sensors (standard-Forehead and alternative-Nasal) Other parameters that will be measure are patient demographics (age, sex, surgery, ASA status, weight, height, BMI).

Registry
clinicaltrials.gov
Start Date
December 1, 2019
End Date
April 1, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Boris Tufegdzic

Asst Prof Dr Boris Tufegdzic

Cleveland Clinic Abu Dhabi

Eligibility Criteria

Inclusion Criteria

  • Patients older than 18 years of age, both genders.
  • Patients undergoing simple or complex surgery.
  • American Society of Anesthesiologists Classification (ASA) score I to III.

Exclusion Criteria

  • American Society of Anesthesiologists Classification (ASA) score IV and V.
  • Emergency cases
  • Cognitive/Mentally impaired or unable to provide consent
  • Previous neurological problems affecting EEG
  • Use of sedative or drugs that can alter EEG readings
  • Patients under head and neck surgery

Outcomes

Primary Outcomes

Validation of nasal SedLine® EEG sensor position for monitoring the depth of anesthesia using processed electroencephalograph values

Time Frame: One year

Determine whether it is possible to apply an alternative SedLine® EEG sensor position in a situation where a standard-forehead position is not possible.

Study Sites (1)

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