NCT01301131Unknown4 期
Randomized Controlled Trial of Fermented Dairy Product Containing L. Casei Shirota for Prevention of Ventilator-Associated Pneumonia
适应症
试验速览
- 阶段
- 4 期
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Number of subjects with pneumonia
研究概览
简要总结
Hospitalized patients with ventilator are randomized to receive fermented dairy product containing L. casei shirota or nothing. The main outcome is development of ventilator-associated pneumonia (VAP)
详细描述
Fermented dairy product containing L. casei shirota has bee shown to inhibit multi-drug-resistant bacteria. This study is conducted to determine if Fermented dairy product containing L. casei shirota can prevent ventilator-associated pneumonia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient age ≥ 18-year who received ventilator and agreed to participate by signing informed consent form
排除标准
- •Immunocompromised host (e.g. HIV infection, On immunosupressive agents, ANC ≤ 500 cell/ml), Pregnancy, History of congenital heart disease, rheumatic fever, previously infective endocarditis, prosthetic valve, Contraindication for enteral feeding, History of milk or milk-product allergy
结局指标
主要结局
Number of subjects with pneumonia
时间窗: up to 28 days
patient with pneumonia
次要结局
未报告次要终点
研究者
Visanu Thamlikitkul
Faculty of Medicine Siriraj Hospital
Mahidol University
研究点 (2)
Loading locations...
相似试验
已完成
不适用
A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)Women With IBS-CNCT01097993Danone Research120
已完成
不适用
Impact of Protein-Enriched Lacto-Vegetarian Soup on Muscle Mass and Muscle Strength Among Older AdultsSarcopeniaMuscle LossMalnutritionNCT05243472Buddhist Tzu Chi General Hospital100
已完成
不适用
Fermented Milk Supplementation on Symptoms of Disease and Treatment in Patients With Multiple MyelomaPlasma Cell MyelomaNCT04530812Roswell Park Cancer Institute13
已完成
不适用
Probiotics Prevent Health Problems in ChildrenGastrointestinal System DiseaseRespiratory SystemNCT04346576National Institute of Nutrition, Vietnam1,036
已完成
不适用
Lactobacillus Casei Strain Shirota Fermented Milk for Alleviating Hard Stools in VietnamConstipationNCT05982743Yakult Honsha Co., LTD51