Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis

Completed

• Conditions: Osteoporosis

• Registration Number: NCT01504230
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury and even mortality. Identifying the factors related to falls occur within this population is essential for the development of effective regimes for fall prevention. The long-term objectives of this work are to ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs. The entire body's center of mass (CoM) is a critical indicator for balance control and the coordination among joints and muscles to control the CoM is still unclear. The aim1 of this study is to develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis. The aim2 of this study is to identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis. The findings of this research can provide needed information regarding the processes of balance control in this vulnerable osteoporosis population, and has the potential to be applied to individuals with other neuromuscular and orthopedic deficits.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-09
• Study First Submitted: 2012-01-03
• Study First Submitted QC: 2012-01-04
• Study First Posted: 2012-01-05
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Status Verified: 2016-12
• Last Update Submitted: 2016-12-15
• Last Update Posted: 2016-12-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• for healthy older adults (OA)

  1. can stand for 5 minutes and walk for 6 minutes independently
  2. normal or corrected to normal vision
  3. an age between 65-85 years
  4. no osteoporosis (T-score above -2.5)

• for osteoporosis participants (OP)

  1. can stand for 5 minutes and walk for 6 minutes independently
  2. normal or corrected to normal vision
  3. an age between 65-85 years
  4. no osteoporosis (T-score below -2.5)

Exclusion Criteria

1. pregnant women
2. cancer diagnosis
3. sensory-motor deficits
4. the BMI is larger than 30 or smaller than 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

School & Graduate Institute of Physical Therapy College of Medicine, National Taiwan University; 🇨🇳 Taipei, Taiwan