og-term follow-up of patients with cerebral AVM-hemorrhage, with particular attention to functional quality of life and socioeconomic status.

Not yet recruiting

• Conditions: Brain AVM , Q28.2Intracerebral Hemorrhage I61.2; Q28.2; I61.2; Arteriovenous malformation of cerebral vessels; Intracerebral haemorrhage in hemisphere, unspecified

• Registration Number: DRKS00017409
• Lead Sponsor: Goethe Universitätsklinik FrankfurtNeurochirurgie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-07-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Arteriovenous Malformation
Follow-up

Exclusion Criteria

No Arteriovenous malformation
lost to follow-up

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main target: extent of quality of life (QOLS) and neurological status after at least 5 years (mRS).<br><br>Determination of the target values ??based on:<br>1. At the time of the event - 2. after at least 6 months - 3. currently (after at least 5 years)<br>- self-produced questionnaire (I.) based on Lampert, Thomas, et al. In this questionnaire, health-influencing parameters are also queried, such as sports activities, smoking status and alcohol consumption of the patient.<br>- QOLS Questionnaire (I.a) in German translation from Offenbacher et al.<br>- Modified Rankin Scale [6]. (Scale from 0-6, interpretation / classification based on the patient's history) - Neurological examination sheet<br>- PHQ-9 (Patient Health Questionnaire, Patient Health Sheet Depression Module).

Secondary Outcome Measures

Name	Time	Method
Outcome measures: To identify risks and prognostic factors that could affect quality of life and clinical outcome.<br><br>Prognostic factors:<br>- Age at first diagnosis and current age<br>- Gender<br>- Infratentorial vs. Supratentorial bleeding<br>- WFNS (World Federation or Neurosurgical Societies)<br>- Intracerebral Hemorrhage Volume<br>- Spetzler Martin degree (AVM localization, size, venous drainage)<br>- Type of bleeding (SAB, ICB, IVH)<br>- AVM associated aneurysms<br>- Therapy type (OP, Endo, Gamma Knife) or therapy / no therapy<br>- Socio-economic status (SES) according to Lampert and Kroll [5] (self-produced questionnaire based on the parameters used in the study: age, gender, region, nationality, education, occupation, income, household characteristics)<br>- Neurological examination sheet<br>- depressive syndromes (PHQ-9, depression module of the patient's health bow)<br>